Radiation-induced Thyroid Cancer—What's New?
نویسندگان
چکیده
منابع مشابه
Radiation-induced senescence-like terminal growth arrest in thyroid cells.
Premature senescence may play an important role as an acute, drug-, or ionizing radiation (IR)-inducible growth arrest program along with interphase apoptosis and mitotic catastrophe. The aim of the study was to evaluate whether IR can induce senescence-like phenotype (SLP) associated with terminal growth arrest in the thyroid cells, and if so, to evaluate impact of terminal growth arrest assoc...
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The risk of developing thyroid cancer increases considerably after exposure to external or internal radiation, especially in children below the age of 10. After the Chernobyl reactor accident, the yearly incidence of childhood thyroid cancer in Belarus increased to approximately 40 per 1.000.000 in girls and to roughly 20 per 1.000.000 in boys compared to approximately 0.5 cases per 1.000.000 p...
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Early investigations, both experimental and clinical, created the impression that the thyroid gland is relatively resistant to injury by ionizing radiation (86, 87). The results of the many studies carried out during the past decade, however, not only have reversed this view, but have, in fact, emphasized that destructive lesions of the gland can be readily produced in man and several species o...
متن کاملComplication of thyroidectomy in patients with radiation-induced thyroid neoplasms.
HYPOTHESIS The complication rate for thyroidectomy is the same in patients with and without a history of radiation exposure. DESIGN Retrospective medical record review of 171 consecutive patients who had a previous history of radiation treatment and had undergone a thyroid operation from 1961 to 1999. SETTING University of California, San Francisco, Medical Center and affiliated hospitals. ...
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Recurrent translocations are well known hallmarks of many human solid tumors and hematological disorders, where patient- and breakpoint-specific information may facilitate prognostication and individualized therapy. In thyroid carcinomas, the proto-oncogenes RET and NTRK1 are often found to be activated through chromosomal rearrangements. However, many sporadic tumors and papillary thyroid carc...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2005
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/dji151